2ER26-1 : Addition of 7-Hydroxymitragynine - (methyl (E)-2[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine (9-O-Demethylmitragynine, 8-OH) - methyl (E)-2-[(2S,3S,12bS)-3-ethyl-8-hydroxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; 10-Hydroxycorynantheidine ((20S)-10-hydroxycorynantheidine, 10-OH) - Methyl (E)-2-[(2S,3S,12bS)-3-ethyl-9-hydroxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; Mitragynine pseudoindoxyl - Methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-3-oxospiro[1H-indole-2, 1'-3, 5, 6, 7, 8, 8a-hexahydro-2H-indolizine, -7'-yl]-3-methoxyprop-2-enoate; 7-Acetoxymitragynine - Methyl (E)-2-[(2S,3S,7aS,12bS)-7a-acetyloxy-3-ethyl-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2, 3-a] quinolizin-2-yl]-3-methoxyprop-2-enoate; Dihydro-7-hydroxymitragynine (MGM-15) - (E)-methyl 2-((2S,3S,7aS,12aR,12bS)-3-ethyl-7a-hydroxy-8-methoxy-1,2,3,4,6,7,7a,12,12a,12b-decahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate; and 9-Fluoro-7-hydroxymitragynine (MGM-16) - (E)-methyl 2-((2S,3S,7aS,12aR,12bS)-3-ethyl-9-fluoro-7a-hydroxy-8-methoxy-1,2,3,4,6,7,7a,12,12a,12b-decahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate; TO SCHEDULE I, SUBSECTION 893.03(1)(a), F.S. - Florida Administrative Rules, Law, Code, Register

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Rule: 2ER26-1 Prev Up Next

Rule Title: Addition of 7-Hydroxymitragynine - (methyl (E)-2[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine (9-O-Demethylmitragynine, 8-OH) - methyl (E)-2-[(2S,3S,12bS)-3-ethyl-8-hydroxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; 10-Hydroxycorynantheidine ((20S)-10-hydroxycorynantheidine, 10-OH) - Methyl (E)-2-[(2S,3S,12bS)-3-ethyl-9-hydroxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; Mitragynine pseudoindoxyl - Methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-3-oxospiro[1H-indole-2, 1'-3, 5, 6, 7, 8, 8a-hexahydro-2H-indolizine, -7'-yl]-3-methoxyprop-2-enoate; 7-Acetoxymitragynine - Methyl (E)-2-[(2S,3S,7aS,12bS)-7a-acetyloxy-3-ethyl-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2, 3-a] quinolizin-2-yl]-3-methoxyprop-2-enoate; Dihydro-7-hydroxymitragynine (MGM-15) - (E)-methyl 2-((2S,3S,7aS,12aR,12bS)-3-ethyl-7a-hydroxy-8-methoxy-1,2,3,4,6,7,7a,12,12a,12b-decahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate; and 9-Fluoro-7-hydroxymitragynine (MGM-16) - (E)-methyl 2-((2S,3S,7aS,12aR,12bS)-3-ethyl-9-fluoro-7a-hydroxy-8-methoxy-1,2,3,4,6,7,7a,12,12a,12b-decahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate; TO SCHEDULE I, SUBSECTION 893.03(1)(a), F.S.
Department:	DEPARTMENT OF LEGAL AFFAIRS	Add to MyFLRules Favorites
Division:	Departmental
Chapter:	Emergency Rule for Year 2026

Latest version of the final adopted rule presented in Florida Administrative Code (FAC):

	Effective Date:	7/1/2026
	History Notes:	Rulemaking Authority 893.035 FS. Law Implemented 893.03, 893.035 FS. History–New 7-1-26.
	References in this version:	No reference(s).

History of this Rule since Jan. 6, 2006

Section	Description	ID	Publish Date

Final 2ER26-1	Addition of 7-Hydroxymitragynine - (methyl (E)-2[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine ....	31051754	Effective: 07/01/2026
Emergency 2ER26-1	Addition of 7-Hydroxymitragynine - (methyl (E)-2[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine ....	31048747	6/24/2026 Vol. 52/122

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